23,810 research outputs found
Magnetic screening properties of an incompressible chiral fluid
We study the possible penetration of a static magnetic field in an idealized
sample of many layers supporting a two dimensional charged chiral quantum
fluid, to see whether there is a kind of Meissner effect. This is a non
standard problem since the quantum fluid is incompressible having a gap in its
spectrum. We find that the system shows an intermediate behaviour between
superconducting and non-superconducting fluids, the magnetic field being
screened or not depending on its orientation relative to the layers.Comment: 20 pages, plain tex, SISSA 50/94/E
Frequency domain state-space system identification
An algorithm for identifying state-space models from frequency response data of linear systems is presented. A matrix-fraction description of the transfer function is employed to curve-fit the frequency response data, using the least-squares method. The parameters of the matrix-fraction representation are then used to construct the Markov parameters of the system. Finally, state-space models are obtained through the Eigensystem Realization Algorithm using Markov parameters. The main advantage of this approach is that the curve-fitting and the Markov parameter construction are linear problems which avoid the difficulties of nonlinear optimization of other approaches. Another advantage is that it avoids windowing distortions associated with other frequency domain methods
Contributions of hyperon-hyperon scattering to subthreshold cascade production in heavy ion collisions
Using a gauged flavor SU(3)-invariant hadronic Lagrangian, we calculate the
cross sections for the strangeness-exchange reactions YY to N\Xi (Y=\Lambda,
\Sigma) in the Born approximation. These cross sections are then used in the
Relativistic Vlasov-Uehling-Uhlenbeck (RVUU) transport model to study \Xi
production in Ar+KCl collisions at incident energy of 1.76A GeV and impact
parameter b=3.5 fm. We find that including the contributions of hyperon-hyperon
scattering channels strongly enhances the yield of \Xi, leading to the
abundance ratio \Xi^{-}/(\Lambda+\Sigma^{0})=3.38E-3, which is essentially
consistent with the recently measured value of by the HADES collaboration at GSI.Comment: 8 pages, 5 figure
Renormalization Group Flow of Four-fermi with Chern-Simons Interaction
We introduce Chern-Simons interaction into the three dimensional four-fermi
theory, ad suggest a possible line of non-Gaussian infrared stable fixed points
of the four-fermi operator, this line is characterized by the Chern-Simons
coupling.Comment: 23 pages, IFT-485-UNC. The is the version to appear in Nucl Phys
Spinon Fermi surface in a cluster Mott insulator model on a triangular lattice and possible application to 1T-TaS
1T-TaS is a cluster Mott insulator on the triangular lattice with 13 Ta
atoms forming a star of David cluster as the unit cell. We derive a two
dimensional XXZ spin-1/2 model with four-spin ring exchange term to describe
the effective low energy physics of a monolayer 1T-TaS, where the effective
spin-1/2 degrees of freedom arises from the Kramers degenerate spin-orbital
states on each star of David. A large scale density matrix renormalization
group simulation is further performed on this effective model and we find a
gapless spin liquid phase with spinon Fermi surface at moderate to large
strength region of four-spin ring exchange term. All peaks in the static spin
structure factor are found to be located on the "" surface of half-filled
spinon on the triangular lattice. Experiments to detect the spinon Fermi
surface phase in 1T-TaS are discussed.Comment: 5+11 pages, 4+13 figure
Modeling pegylated liposomal doxorubicin-induced hand-foot syndrome and intestinal mucositis in zebrafish
[[abstract]]Pegylated liposomal doxorubicin (PLD) has been widely used to treat cancer. The adverse effects of PLD noted in clinical practice, especially hand-foot syndrome (HFS), are regarded as unique, and the management methods for them remain limited. This study was aimed at developing a feasible experimental model for translational medicine to solve this clinical issue by using skin fluorescent transgenic zebrafish. We established an optimal protocol for the administration of Lipo-Dox™, a PLD in current clinical use, to the Tg(k18:dsred) zebrafish line expressing red fluorescence in keratinocytes. We made use of bodyweight, survival rate, gross observation, flssuorescent microscopic assessment, and pathological examination of the zebrafish to assess this model. The consecutive administration protocol of PLD resulted in growth retardation of the zebrafish embryo and survival impairment, indicating establishment of a significant toxicity. We observed fin necrosis and keratinocyte dissociation phenotypes in the PLD-treated fish after consecutive administration. The skin toxicity induced by the Lipo-Dox injection was subsequently reversible, which might be compatible with a clinical course of skin recovery after discontinuation of Lipo-Dox administration. Furthermore, we found that the number of intestinal goblet cells, an important marker of intestinal inflammation, in the Lipo-Dox-injected zebrafish was markedly increased, accompanied by impaired mucosal integrity. The intestinal inflammation induced by Lipo-Dox resembled the intestinal mucositis the clinical patients suffered from after the administration of PLD. In conclusion, we established a zebrafish model for PLD-induced HFS. The intestinal mucositis simultaneously noted in the PLD-treated zebrafish validated the similarity of clinical courses after administration of PLD. This model is easily assessable, efficient, and worthy for use in developing a new therapeutic protocol for prevention or treatment of HFS as well as intestinal mucositis. Further clinical investigations to validate the correlation between human and zebrafish data are warranted.[[journaltype]]國外[[ispeerreviewed]]Y[[booktype]]電子版[[countrycodes]]GB
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